Sampling of dermal Interstitial Fluid (dISF)

Application Areas

With the tremendous breakthroughs achieved in analysis methods, the guidance received from number crunching apps and the awareness that comes from our connected modern lifestyle with a smart device always at arm’s reach; The missing link has been the very first part of the chain - How to get biomarkers out of the body using methods compatible with our modern way of life?

The need for biomarkers

Wherever there is a need for biomarker analysis there is a use case for sampling of dermal interstitial fluid using Ascilion’s technology and products. Using hollow microneedles for sampling is quick, easy, requires a minimum of post processing of the sample and leaves no scarring or itching.

Ascilion’s products will facilitate biomarker discovery and enable improved diagnostics.

Clinical Research

Targeted disease treatment requires advanced diagnostics and thus a thorough understanding of biomarkers – often in the interstitial compartment. For instance, dermatology and allergology researchers can now access the fluid compartment most suitable for cytokine analysis.

Ascilion has together with partners demonstrated that dermal interstitial fluid contains local tissue-specific biomarkers that are difficult to detect in blood plasma or serum.

Pharmaceutical Development

Studies that previously couldn’t be performed due to inherent limitations of microdialysis extraction of biomolecules or creation of suction blisters are now possible, even with the aim of studying pharmacokinetics.

Precision medicine involves tailoring disease prevention and treatment. Interstitial fluid analysis deepens the understanding of precision medicine.

Cosmetics

The system can be used in clinical safety and efficacy studies of skin treatment products intended for cosmetic use. Sampling can be done in parallel on provoked and unprovoked skin areas for comparison.

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Sampling of dermal Interstitial Fluid (dISF)

Application Areas

The need for biomarkers

Ascilion’s products will facilitate biomarker discovery and enable improved diagnostics.

Clinical Research

Pharmaceutical Development

Cosmetics

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Get in touch

Get in touch